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An ever-ambitious company Reinvention is in our blood (we are a science company, after all). From the depths of the Dutch State Mines over a century ago we've transformed ourselves into something truly bright: a global science-based company specializing in ensuring the world is healthier, happier and safer.


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Bart Welten Chief Financial Officer Bart Welten (Dutch) holds a law degree from Leiden University (Netherlands) and an MBA from Boston College (USA). Bart started his career as a management consultant in Amsterdam and later joined Royal Gist-brocades in Delft.


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2 International Regulatory Affairs, DSM/Gist-brocades, Delft, Netherlands Corresponding Author: International Regulatory Affairs, DSM/Gist-brocades B.V., Business Group, Anti-Infectives, PO Box 1, 2600 MA Delft, The Netherlands


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Abstract The enzyme glucose isomerase used by Gist‐Brocades for the process of immobilization is derived from a strain of Actinoplanes missouriensis. The intracellular enzyme is fixed to the mycelium and as such immobilized.


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Through the $1.4 billion acquisition of Gist­ brocades {Delft, The Netherlands) by the chemicals firm DSM (Heerlen, The Neth-erlands), a new anti-biotics intermediates


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3 International Regulatory Affairs, DSM/Gist-brocades, Delft, Netherlands Corresponding Author: International Regulatory Affairs, DSM/Gist-brocades, Business Group Anti-Infectives, PO Box 1, 2600 MA Delft, The Netherlands


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The 'Grote Kantoor', completed in 1907, is a national monument and served until 1998 as the headquarters of the Gist-Brocades company. Get in touch. About campus. Open innovation. Map Biotech Campus Delft Travel directions Parking.


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Gist Brocades N. V., Research and Development, P.O. Box 1 2600 MA Delft, The Netherlands. Gist Brocades N. V., Research and Development, P.O. Box 1 2600 MA Delft, The NetherlandsSearch for more papers by this author


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Gist-brocades is a major international biotechnology company with its main production facilities in Delft. Waste water from the various fermentation and chemical production processes is characterized by its high concentration and frequent fluctuation of pollution components.


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goals of a totally novel wastewater treatment at the Gist Brocades biotechnological factory in Delft. The concept developed by Sef Heijnen (Heijnen et al., 1991) was a series of fluidized bed reactors (vertical cylindrical columns of 18 m high and 5 m in diameter) with suspended flocs or granules of microorganisms initially attached to sand.


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During World War II researchers worked on penicillin. The code name Bacinol was used to keep the research secret from the Germans. [6] The research was done at the company Nederlandsche Gist- en Spiritusfabriek, Dutch Yeast and Spirits Factory, later becoming DSM Sinochem Pharmaceuticals, in Delft .


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The sprawling industrial complex that is the Nederlandsche Gisten en Spiritusfabriek lies between the railway and the canals is not the most beautiful sight in Delft but nevertheless it has a fascinating history and an aspect that justifies its inclusion in this column.


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In the early 1990s, the Gist Brocades Fermentation Company closed their pilot plant, leaving the reactor in our laboratory as the only confirmed source of anammox bacteria.. Delft University of.


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In 1968 the Dutch Yeast and Spirits Factory merged with Brocades to form the Royal Gist-Brocades NV. In 1998 the Royal Gist-Brocades NV was taken over by multinational DSM. In 2019, DSM in Delft celebrated its 150 anniversary and being a front runner in biotechnological innovations with global impact.